Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307147 | 0.91 | MTNR1A (0.38) | MTNR1AMTNR1BKMT2AMEN1ELANE | |
| SCHEMBL9307145 | 0.82 | MTNR1A (0.42) | MTNR1AMTNR1BKMT2AMEN1ELANE | |
| SCHEMBL10893579 | 0.82 | MTNR1A (0.39) | MTNR1AMTNR1BKMT2AMEN1ESR1 | |
| SCHEMBL9307174 | 0.81 | MTNR1A (0.38) | MTNR1AMTNR1BKMT2AESR1MAPT | |
| SCHEMBL8972338 | 0.79 | HDAC3 (0.46) | KMT2AMEN1MAPT | |
| SCHEMBL10891092 | 0.78 | MTNR1A (0.38) | MTNR1AMTNR1BKMT2AMEN1ELANE | |
| SCHEMBL10892695 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BKMT2AELANEESR1 | |
| Ammonia Solution, Strong SCHEMBL10865678 | 0.77 | HDAC3 (0.45) | KMT2AMEN1MAPT | |
| Dimethylamine SCHEMBL10893057 | 0.77 | HDAC4 (0.45) | KMT2AMEN1MAPT | |
| SCHEMBL10890475 | 0.76 | CTSA (0.42) | MTNR1AMTNR1BKMT2AMEN1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5347008-A | Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents | CIBA-GEIGY CORPORATION (US) | 1994-09-13 | — | — | US | disclosed |
| US-5152929-A | Corrosion inhibitors for water systems | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |