Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307226 | 1.00 | SIGMAR1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL9307221 | 1.00 | SIGMAR1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL7382531 | 0.90 | SIGMAR1 (0.49) | SIGMAR1HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL28748526 | 0.87 | PRCP (0.46) | SIGMAR1HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL10724594 | 0.86 | HTR2A (0.49) | SIGMAR1HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL1724839 | 0.86 | SIGMAR1 (0.49) | SIGMAR1HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1722276 | 0.84 | SIGMAR1 (0.50) | SIGMAR1HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL7376647 | 0.84 | HTR2C (0.42) | SIGMAR1HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL691797 | 0.83 | MEN1 (0.49) | HTR2AHTR2CHTR2BTAAR1 | |
| SCHEMBL5871094 | 0.82 | SIGMAR1 (0.49) | SIGMAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294618-A | Psychological disorders | MERCK SHARP & DOHME LIMITED (GB) | 1994-03-15 | — | — | US | disclosed |
| EP-0410535-A2 | Octahydrobenzisoquinoline derivatives as antipsychotic agents | MERCK SHARP & DOHME LTD. (GB) | 1991-01-30 | — | — | EP | disclosed |