Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7393691 | 0.91 | ITGB3 (0.60) | ITGB3ITGA2BKDM4EKMT2ANPC1 | |
| SCHEMBL7294444 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BKDM4EKMT2ANPC1 | |
| SCHEMBL9156861 | 0.83 | ITGB3 (0.42) | ITGB3ITGA2BKDM4EKMT2ANPC1 | |
| SCHEMBL7391463 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BPPARGPPARDPPARA | |
| SCHEMBL7291522 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BPPARGPPARDPPARA | |
| SCHEMBL7417689 | 0.81 | CA12 (0.48) | ITGB3ITGA2BMAPT | |
| SCHEMBL7431233 | 0.81 | CA12 (0.48) | ITGB3ITGA2BMAPT | |
| SCHEMBL7421813 | 0.81 | CA12 (0.48) | ITGB3ITGA2BMAPT | |
| SCHEMBL7422118 | 0.81 | CA12 (0.48) | ITGB3ITGA2BMAPT | |
| SCHEMBL7386323 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BPPARGLTA4HPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | claimed |
| US-5294616-A | Anticoagulants, inhibition of fibrinogen binding to blood platelets | MERCK & CO., INC. (US) | 1994-03-15 | — | — | US | disclosed |