Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9159728 | 0.95 | PPARG (0.50) | PPARAPPARG | |
| SCHEMBL9307393 | 0.92 | PPARA (0.52) | PPARAPPARG | |
| SCHEMBL9165348 | 0.86 | PPARG (0.48) | PPARAPPARG | |
| SCHEMBL9165031 | 0.85 | PPARG (0.41) | PPARAPPARG | |
| SCHEMBL9138986 | 0.83 | EDNRA (0.52) | PPARAPPARG | |
| SCHEMBL9165323 | 0.81 | PPARA (0.44) | PPARA | |
| SCHEMBL9168065 | 0.79 | PPARG (0.40) | PPARAPPARG | |
| SCHEMBL9126457 | 0.79 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL7331714 | 0.78 | PPARG (0.49) | PPARAPPARG | |
| SCHEMBL9307631 | 0.78 | EDNRB (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374638-A | Cardiovascular disorders, hypotensive agents | MERCK & CO., INC. (US) | 1994-12-20 | — | — | US | disclosed |