Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165031 | 0.92 | PPARG (0.41) | PPARGPPARAADRB3ADRB1EDNRB | |
| SCHEMBL9165348 | 0.89 | PPARG (0.48) | PPARGPPARAADRB3ADRB1 | |
| SCHEMBL7410289 | 0.88 | PPARG (0.50) | PPARGPPARAEDNRBEDNRA | |
| SCHEMBL9307393 | 0.86 | PPARA (0.52) | PPARGPPARAADRB3ADRB1 | |
| SCHEMBL9168061 | 0.83 | ADRB3 (0.40) | ADRB3ADRB1ADRB2GLA | |
| SCHEMBL9159728 | 0.82 | PPARG (0.50) | PPARGPPARA | |
| SCHEMBL7414833 | 0.81 | PPARG (0.51) | PPARGPPARAEDNRBEDNRA | |
| SCHEMBL9307429 | 0.79 | PPARA (0.53) | PPARGPPARA | |
| SCHEMBL9051202 | 0.78 | EDNRB (0.55) | PPARGPPARAEDNRBEDNRA | |
| SCHEMBL7408292 | 0.78 | PPARG (0.50) | PPARGPPARAEDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420133-A | Quinazolinones substituted with phenoxyphenylacetic acid derivatives | MERCK & CO., INC. (US) | 1995-05-30 | — | — | US | disclosed |