Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18631541 | 0.81 | KMT2A (0.47) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL2977751 | 0.81 | KMT2A (0.47) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL11879067 | 0.81 | MCL1 (0.53) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL5551751 | 0.79 | KMT2A (0.45) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL195764 | 0.76 | KMT2A (0.51) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL2967926 | 0.75 | KMT2A (0.54) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL11553590 | 0.73 | MAPT (1.00) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL11303565 | 0.73 | DAO (0.68) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL1238984 | 0.73 | DAO (1.00) | KDM4EKMT2AMAPTALDH1A1HPGD | |
| SCHEMBL10103705 | 0.71 | KMT2A (0.76) | KDM4EKMT2AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340818-A | Treating leukemia with acridine-9-one derivative(glyfoline) | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-08-23 | — | — | US | disclosed |