Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581156 | 0.87 | KMT2A (1.00) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL214075 | 0.87 | KMT2A (1.00) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL8304311 | 0.85 | KMT2A (0.81) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11687991 | 0.83 | KMT2A (0.92) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL28888813 | 0.82 | KMT2A (0.59) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL11685259 | 0.82 | KMT2A (0.70) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9574636 | 0.82 | KMT2A (0.59) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL30078373 | 0.82 | MAPT (0.67) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL9241728 | 0.82 | MAPT (0.67) | KMT2AMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL3686929 | 0.82 | KMT2A (0.76) | KMT2AMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319951-B1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND FOR THE PREPARATION OF PRODUCTS DERIVED FROM SAME, PARTICULARLY FROM AMBROX | BASF SE (DE) | 2021-09-08 | — | — | EP | disclosed |
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | BASF SE (DE) | 2019-06-11 | — | — | US | disclosed |
| WO-2017009205-A1 | METHOD FOR THE HYDROFORMYLATION OF 2-SUBSTITUTED BUTADIENES AND THE PRODUCTION OF SECONDARY PRODUCTS THEREOF, ESPECIALLY AMBROX | BASF SE (DE) | 2017-01-19 | — | — | WO | disclosed |
| US-9266808-B2 | Method for the hydroformylation of olefins | BASF SE (DE) | 2016-02-23 | — | — | US | disclosed |
| US-9266808-B2 | Method for the hydroformylation of olefins | BASF SE (DE) | 2016-02-23 | — | — | US | disclosed |
| US-8853425-B2 | Process for the preparation of benzodithiophene compounds | ENI S.P.A. (IT) | 2014-10-07 | — | — | US | disclosed |
| US-8853425-B2 | Process for the preparation of benzodithiophene compounds | ENI S.P.A. (IT) | 2014-10-07 | — | — | US | disclosed |
| EP-2769981-A1 | Improved process for the preparation of benzodithiophene compounds | ENI S.p.A. (IT) | 2014-08-27 | — | — | EP | disclosed |
| US-20140235874-A1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | ENI S.P.A (IT) | 2014-08-21 | — | — | US | disclosed |
| US-20140235874-A1 | PROCESS FOR THE PREPARATION OF BENZODITHIOPHENE COMPOUNDS | ENI S.P.A (IT) | 2014-08-21 | — | — | US | disclosed |
| US-8110709-B2 | Stabilization of hydroformylation catalysts based on phosphoramide ligands | BASF SE (DE) | 2012-02-07 | — | — | US | disclosed |
| EP-1677911-B1 | STABILIZATION OF HYDROFORMYLATION CATALYSTS BASED ON PHOSPHORAMIDE LIGANDS | BASF SE (DE) | 2010-06-16 | — | — | EP | disclosed |
| US-20100048959-A1 | METHOD FOR THE HYDROFORMYLATION OF OLEFINS | BASF SE (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20100048959-A1 | METHOD FOR THE HYDROFORMYLATION OF OLEFINS | BASF SE (DE) | 2010-02-25 | — | — | US | disclosed |
| US-20090227801-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-10 | — | — | US | disclosed |
| US-20090227801-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | BASF AKTIENGESELLSCHAFT (DE) | 2009-09-10 | — | — | US | disclosed |
| EP-1539666-B1 | METHOD FOR PRODUCING DIALDEHYDES AND/OR ETHYLENICALLY UNSATURATED MONOALDEHYDES BY HYDROFORMYLATING ETHYLENICALLY UNSATURATED COMPOUNDS | BASF SE (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2008065171-A1 | METHOD FOR THE HYDROFORMYLATION OF OLEFINS | BASF SE (DE) | 2008-06-05 | — | — | WO | disclosed |
| US-7173138-B2 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-06 | — | — | US | disclosed |
| US-7173138-B2 | Ligands for pnicogen chelate complexes with a metal of subgroup VIII and use of the complexes as catalysts for hydroformylation, carbonylation, hydrocyanation or hydrogenation | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10315975-B2 | Method for the hydroformylation of 2-substituted butadienes and the production of secondary products thereof, especially ambrox | ALOX12, ALOX15, ALOX5 | KMT2A 2777/4885MAPT 4615/4885ALDH1A1 683/4885 |
| US-20090227801-A1 | LIGANDS FOR USE IN ASYMMETRIC HYDROFORMYLATION | PFKFB3, PHPT1, PFKFB4 | KMT2A 2660/4885MAPT 3930/4885ALDH1A1 2413/4885 |
| US-20100048959-A1 | METHOD FOR THE HYDROFORMYLATION OF OLEFINS | DOHH, CYP4F3, DHPS | KMT2A 3485/4885MAPT 4180/4885ALDH1A1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.