SCHEMBL9307612

SCHEMBL9307612

COC(=O)c1cc(C(=O)C(OC(C)C)OC(C)C)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.53
CA1 P00915 5/20 0.53
CA2 P00918 5/20 0.53
CA7 P43166 5/20 0.53
CA9 Q16790 5/20 0.53
CA14 Q9ULX7 5/20 0.53
XDH P47989 1/20 0.46
PTGS2 P35354 1/20 0.44
HPGD P15428 3/20 0.44
HSD17B10 Q99714 3/20 0.44
TSHR P16473 2/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 4/20 0.42
GAA P10253 3/20 0.42
DBH P09172 1/20 0.42
RECQL P46063 1/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9383996 0.85 CSNK2A1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL9308620 0.84 KDM4E (0.44) CA12CA1CA2CA7CA9
SCHEMBL10728488 0.82 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL4863627 0.81 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL403210 0.79 CA12 (0.71) CA12CA1CA2CA7CA9
SCHEMBL31258831 0.76 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL330670 0.76 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL1647438 0.76 CA12 (0.65) CA12CA1CA2CA7CA9
SCHEMBL4424415 0.74 CA1 (0.62) CA12CA1CA2CA7CA9
SCHEMBL12040097 0.73 CA12 (0.61) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548224-B1 PROCESS FOR PREPARING ALBUTEROL, ACETAL, HEMI-ACETAL, AND HYDRATES OF ARYLGLYOXAL INTERMEDIATES THEREOF SCHERING CORP (US) 1994-11-23 EP claimed
US-5283359-A Process for preparing albuterol, acetal, hemi-acetal, and hydrates of arylglyoxal intermediates thereof SCHERING CORP. (US) 1994-02-01 US claimed
EP-0548224-A1 PROCESS FOR PREPARING ALBUTEROL, ACETAL, HEMI-ACETAL, AND HYDRATES OF ARYLGLYOXAL INTERMEDIATES THEREOF. SCHERING CORP (US) 1993-06-30 EP claimed
WO-1992004314-A2 PROCESS FOR PREPARING ALBUTEROL, ACETAL, HEMI-ACETAL, AND HYDRATES OF ARYLGLYOXAL INTERMEDIATES THEREOF SCHERING CORPORATION (US) 1992-03-19 WO claimed