Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311424 | 0.87 | KMT2A (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ACHRNB2 | |
| SCHEMBL9307811 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP2 | |
| SCHEMBL9028712 | 0.83 | GAA (0.50) | ALDH1A1SMN1; SMN2KMT2ACHRNB2CHRNB4 | |
| SCHEMBL29935439 | 0.82 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP2 | |
| SCHEMBL9027917 | 0.81 | MEN1 (0.48) | ALDH1A1MEN1KMT2AMMP2KDM4E | |
| SCHEMBL9027922 | 0.81 | MEN1 (0.48) | ALDH1A1MEN1KMT2AMMP2KDM4E | |
| SCHEMBL9308729 | 0.78 | HPGD (0.58) | ALDH1A1MEN1KMT2AHPGDKDM4E | |
| SCHEMBL4368576 | 0.74 | ATM (0.59) | ALDH1A1MEN1KMT2AMMP2MAPT | |
| SCHEMBL10390327 | 0.74 | KMT2A (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP2 | |
| SCHEMBL13326445 | 0.74 | KMT2A (0.60) | ALDH1A1SMN1; SMN2MEN1KMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332735-A | Antiamnesic activity | ADIR ET COMPAGNIE (FR) | 1994-07-26 | — | — | US | disclosed |