Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.56 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307857 | 1.00 | GABBR2 (0.56) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL8072535 | 0.83 | GABBR2 (0.58) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL8072537 | 0.83 | GABBR2 (0.58) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL31375211 | 0.83 | GABBR2 (0.58) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL1821480 | 0.82 | PTGS1 (0.74) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL1821479 | 0.82 | PTGS1 (0.74) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL7964070 | 0.77 | GABBR2 (0.59) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL11674975 | 0.76 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL13862271 | 0.76 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2ALOX5 | |
| SCHEMBL20629917 | 0.76 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352677-A | Antihyperlipidemic agents | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-10-04 | — | — | US | disclosed |
| US-5294624-A | Antiartheriosclerosis | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5294643-A | Cinnamamide derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0407200-A1 | Cinnamamide derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-09 | — | — | EP | disclosed |