SCHEMBL9307905

SCHEMBL9307905

NCC(CN)CCCCOc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.61
TAAR1 Q96RJ0 1/20 0.55
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
LTA4H P09960 2/20 0.48
PLA2G2A P14555 1/20 0.48
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
ALDH1A1 P00352 1/20 0.45
RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28567086 0.81 KCNA3 (0.61) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL3953285 0.80 KCNA3 (0.67) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL23151885 0.78 KCNA3 (0.64) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL6245903 0.78 KCNA3 (0.64) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL1490164 0.78 KCNA3 (1.00) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL11876955 0.78 LTA4H (0.47) TAAR1LTA4HDRD2DRD3ALDH1A1
SCHEMBL2528 0.77 KCNA3 (0.76) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL5679133 0.77 KCNA3 (0.61) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL5683038 0.77 KCNA3 (0.61) KCNA3TAAR1HDAC3HDAC4HDAC1
SCHEMBL2512157 0.76 KCNA3 (0.94) KCNA3TAAR1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5302370-A Form complexes with rhenium and technetium INSTITUT FUR DIAGNOSTIKFORSCHUNG GMBH (DE) 1994-04-12 US disclosed
EP-0381713-B1 DIAMINEDITHIOL CHELATING AGENTS FOR RADIOPHARMACEUTICALS MALLINCKRODT INC (US) 1994-01-19 EP disclosed
EP-0381713-A4 DIAMINEDITHIOL CHELATING AGENTS FOR RADIOPHARMACEUTICALS 1991-05-08 EP disclosed
EP-0381713-A1 DIAMINEDITHIOL CHELATING AGENTS FOR RADIOPHARMACEUTICALS. MALLINCKRODT INC (US) 1990-08-16 EP disclosed
WO-1989010759-A1 DIAMINEDITHIOL CHELATING AGENTS FOR RADIOPHARMACEUTICALS MALLINCKRODT, INC. (US) 1989-11-16 WO disclosed