Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337357 | 0.82 | LCK (0.55) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1805788 | 0.82 | LCK (0.55) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9307486 | 0.82 | KDM4E (0.41) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9308590 | 0.80 | KDM4E (0.42) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9306442 | 0.79 | KDM4E (0.42) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1806660 | 0.79 | KDM4E (0.59) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31753892 | 0.78 | CHUK (0.45) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4863627 | 0.77 | CA12 (0.59) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL9308620 | 0.77 | KDM4E (0.44) | CHUKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL322274 | 0.77 | PKM (0.52) | CHUKKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051759-C | Method for preparing aryl ethanolamine | SCHERING CORP (US) | 2000-04-26 | — | — | CN | disclosed |
| CN-1223250-A | Process for preparing acetals Hemi-acetals, and hydrates of arylglyoxals | SCHERING CORP (US) | 1999-07-21 | — | — | CN | disclosed |
| EP-0548224-B1 | PROCESS FOR PREPARING ALBUTEROL, ACETAL, HEMI-ACETAL, AND HYDRATES OF ARYLGLYOXAL INTERMEDIATES THEREOF | SCHERING CORP (US) | 1994-11-23 | — | — | EP | disclosed |
| US-5283359-A | Process for preparing albuterol, acetal, hemi-acetal, and hydrates of arylglyoxal intermediates thereof | SCHERING CORP. (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0548224-A1 | PROCESS FOR PREPARING ALBUTEROL, ACETAL, HEMI-ACETAL, AND HYDRATES OF ARYLGLYOXAL INTERMEDIATES THEREOF. | SCHERING CORP (US) | 1993-06-30 | — | — | EP | disclosed |
| CN-1059904-A | Preparation method of salbutamol and intermediate thereof | SCHERING CORP (US) | 1992-04-01 | — | — | CN | disclosed |
| WO-1992004314-A2 | PROCESS FOR PREPARING ALBUTEROL, ACETAL, HEMI-ACETAL, AND HYDRATES OF ARYLGLYOXAL INTERMEDIATES THEREOF | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |