Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305376 | 0.94 | PARP1 (0.42) | RAD52PARP1GPR84CTSVCTSL | |
| SCHEMBL8540141 | 0.90 | PARP1 (0.43) | PARP1GPR84CTSVCTSLGSK3B | |
| SCHEMBL9164367 | 0.87 | KDM4E (0.45) | PARP1GPR84CTSVCTSLGSK3B | |
| SCHEMBL9423361 | 0.86 | PARP1 (0.42) | PARP1GPR84CTSVCTSLGSK3B | |
| SCHEMBL9378774 | 0.85 | PARP1 (0.43) | PARP1GPR84CTSVCTSLGSK3B | |
| SCHEMBL8545291 | 0.85 | PARP1 (0.43) | PARP1GPR84CTSVCTSLGSK3B | |
| SCHEMBL9374556 | 0.81 | GSK3B (0.39) | PARP1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL9052175 | 0.80 | MAPT (0.59) | PARP1TSHRGSK3BMAPTHTT | |
| SCHEMBL9169194 | 0.79 | PARP1 (0.42) | PARP1GPR84CTSVCTSL | |
| SCHEMBL8538920 | 0.79 | PARP1 (0.45) | PARP1GPR84TSHRGSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294611-A | Hypotensive, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-03-15 | — | — | US | disclosed |