Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 14/20 | 0.43 |
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129724 | 0.92 | PPARG (0.44) | EDNRBEDNRAPPARGPPARAKDM4E | |
| SCHEMBL9127085 | 0.91 | EDNRB (0.51) | EDNRBEDNRAPPARGPPARA | |
| SCHEMBL9128470 | 0.86 | PPARG (0.47) | EDNRBEDNRAPPARGPPARAKDM4E | |
| SCHEMBL9126741 | 0.85 | PPARG (0.47) | EDNRBEDNRAPPARGPPARAKDM4E | |
| SCHEMBL9128656 | 0.79 | ELANE (0.38) | EDNRAPPARAKDM4EALDH1A1MAPT | |
| SCHEMBL7331707 | 0.78 | EDNRA (0.48) | EDNRBEDNRA | |
| SCHEMBL7333563 | 0.78 | EDNRA (0.57) | EDNRBEDNRAPPARGPPARA | |
| SCHEMBL7414833 | 0.74 | PPARG (0.51) | EDNRBEDNRAPPARGPPARAKDM4E | |
| SCHEMBL7410289 | 0.73 | PPARG (0.50) | EDNRBEDNRAPPARGPPARAKDM4E | |
| SCHEMBL7408292 | 0.73 | PPARG (0.50) | EDNRBEDNRAPPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374638-A | Cardiovascular disorders, hypotensive agents | MERCK & CO., INC. (US) | 1994-12-20 | — | — | US | disclosed |