Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308944 | 0.92 | AGTR1 (0.69) | AGTR1PPARG | |
| SCHEMBL9308892 | 0.91 | AGTR1 (0.62) | AGTR1 | |
| SCHEMBL9311500 | 0.85 | AGTR1 (0.49) | AGTR1KDM4ECYP2C9FPR1GAA | |
| SCHEMBL9309558 | 0.84 | AGTR1 (0.56) | AGTR1PPARG | |
| SCHEMBL9309816 | 0.80 | AGTR1 (0.63) | AGTR1 | |
| SCHEMBL1895309 | 0.79 | KDM4E (0.41) | KDM4ECYP2C9FPR1GAACYP2D6 | |
| SCHEMBL1894719 | 0.79 | KDM4E (0.40) | AGTR1KDM4ECYP2C9FPR1GAA | |
| SCHEMBL9308894 | 0.79 | AGTR1 (0.53) | AGTR1PPARG | |
| SCHEMBL9310836 | 0.78 | PPARG (0.40) | PPARG | |
| SCHEMBL9310965 | 0.78 | PPARG (0.40) | AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |