Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.67 |
| ▸ | THRA | P10827 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748616 | 0.88 | THRB (0.55) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL28035844 | 0.87 | THRB (0.61) | THRBTHRATSHRHPGDLIPG | |
| SCHEMBL10824963 | 0.87 | THRB (0.72) | THRBTHRATSHRHPGDLIPG | |
| SCHEMBL3259951 | 0.87 | THRB (0.72) | THRBTHRATSHRHPGDLIPG | |
| SCHEMBL4595925 | 0.82 | THRB (0.58) | THRBTHRATSHRHPGDLIPG | |
| Acrylic Acid Ethyl Ester SCHEMBL28230345 | 0.82 | THRB (0.62) | THRBTHRATSHRHPGDLIPG | |
| SCHEMBL28839036 | 0.81 | THRB (0.55) | THRBTHRATSHRHPGDLIPG | |
| Water SCHEMBL27505131 | 0.81 | THRB (0.58) | THRBTHRATSHRHPGDMEN1 | |
| SCHEMBL28338758 | 0.80 | THRB (0.57) | THRBTHRATSHRHPGDALDH1A1 | |
| SCHEMBL2289077 | 0.80 | THRB (1.00) | THRBTHRALIPGMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330686-A | Crosslinked acrylic ester polymer, benzoxazine compound | PPG INDUSTRIES, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| WO-1994004952-A1 | TEMPERATURE STABLE AND SUNLIGHT PROTECTED PHOTOCHROMIC ARTICLES | PPG INDUSTRIES, INC. (US) | 1994-03-03 | — | — | WO | disclosed |