Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.52 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040631 | 0.84 | TAAR1 (0.54) | CD274PDCD1PTPRCGABRA1GABRB2 | |
| SCHEMBL26613458 | 0.78 | PTPRC (0.53) | CD274PDCD1PTPRCGABRA1GABRB2 | |
| SCHEMBL6048484 | 0.77 | GABRA1 (0.49) | CD274PDCD1PTPRCGABRA1GABRB2 | |
| SCHEMBL27466656 | 0.77 | BCL2L1 (0.59) | CD274PDCD1PTPRCGABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL6048595 | 0.76 | GABRA1 (0.48) | CD274PDCD1PTPRCGABRA1GABRB2 | |
| SCHEMBL31366955 | 0.73 | PTPRC (0.55) | PTPRCNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL3597253 | 0.73 | PTPRC (0.55) | CD274PDCD1PTPRCGABRA1GABRB2 | |
| SCHEMBL5282347 | 0.73 | PTPRC (0.55) | CD274PDCD1PTPRCGABRA1GABRB2 | |
| SCHEMBL395611 | 0.73 | PTPRC (0.55) | PTPRCNPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL429540 | 0.73 | DPP4 (0.58) | CD274PDCD1ALDH1A1BCL2L1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292901-A | Benzodioxole derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| EP-0281098-B1 | BENZODIOXOLE DERIVATIVES, COMPOSITIONS COMPRISING THE SAME, AND THE USE OF THE SAME FOR THE MANUFACTURE OF MEDICAMENTS | Eisai Co., Ltd. (JP) | 1992-11-25 | — | — | EP | disclosed |
| EP-0281098-A1 | Benzodioxole derivatives, compositions comprising the same, and the use of the same for the manufacture of medicaments | Eisai Co., Ltd. (JP) | 1988-09-07 | — | — | EP | disclosed |