Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Methylpyrrolidone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpyrrolidone SCHEMBL28550762 | 0.95 | BRD4 (0.90) | — | |
| Methylpyrrolidone SCHEMBL28847596 | 0.95 | — | — | |
| Methylpyrrolidone SCHEMBL11304311 | 0.95 | BRD4 (0.90) | — | |
| Methylpyrrolidone SCHEMBL27917614 | 0.95 | BRD4 (0.90) | — | |
| Methylpyrrolidone SCHEMBL17709418 | 0.95 | — | — | |
| Methylpyrrolidone SCHEMBL28665050 | 0.95 | — | — | |
| Methylpyrrolidone SCHEMBL28659452 | 0.95 | BRD4 (0.90) | — | |
| Methylpyrrolidone SCHEMBL28250382 | 0.95 | BRD4 (0.90) | — | |
| Methylpyrrolidone SCHEMBL487 | 0.95 | — | — | |
| Methylpyrrolidone SCHEMBL1255511 | 0.95 | BRD4 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112933739-B | Filter screen, preparation method of filter screen and filter device applying filter screen | 宁波方太厨具有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-112933739-A | Filter screen, preparation method of filter screen and filter device applying filter screen | 宁波方太厨具有限公司 | 2021-06-11 | — | — | CN | claimed |
| US-5360636-A | Method for coating cellulosic membranes | AKZO NV (NL) | 1994-11-01 | — | — | US | claimed |
| CN-115349165-A | Method for producing inorganic solid pattern and inorganic solid pattern | 东丽株式会社 | 2022-11-15 | — | — | CN | disclosed |
| CN-112933739-B | Filter screen, preparation method of filter screen and filter device applying filter screen | 宁波方太厨具有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-112933739-A | Filter screen, preparation method of filter screen and filter device applying filter screen | 宁波方太厨具有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112851958-A | Graphene in-situ polymerization semi-aromatic polyamide and preparation method thereof | 常州恒利宝纳米新材料科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| US-5147553-A | Separation of fluid mixture | IONICS, INCORPORATED (US) | 1992-09-15 | — | — | US | disclosed |