Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9306999 | 0.88 | POLB (0.39) | MAPTTP53MEN1LMNAKMT2A | |
| Iodide SCHEMBL9308013 | 0.85 | MEN1 (0.38) | MAPTMEN1NR1I2LMNACHRM2 | |
| Iodide SCHEMBL9308335 | 0.85 | MAPT (0.44) | MAPTMEN1NR1I2LMNACHRM2 | |
| Iodide SCHEMBL9306921 | 0.85 | TP53 (0.49) | MAPTTP53MEN1KMT2ATHRB | |
| Iodide SCHEMBL9307106 | 0.85 | MAPT (0.40) | MAPTTP53MEN1NR1I2LMNA | |
| Iodide SCHEMBL9307671 | 0.84 | TP53 (0.42) | MAPTTP53MEN1KMT2A | |
| Iodide SCHEMBL9306256 | 0.80 | TP53 (0.46) | MAPTTP53LMNA | |
| Iodide SCHEMBL9308401 | 0.80 | LMNA (0.45) | MAPTLMNATHRA | |
| Iodide SCHEMBL9308232 | 0.80 | TP53 (0.49) | MAPTTP53THRBTHRA | |
| Iodide SCHEMBL9307746 | 0.79 | MAPT (0.42) | MAPTMEN1NR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328921-A | Antagonist of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1994-07-12 | — | — | US | disclosed |