Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.58 |
| ▸ | TUBB | P07437 | 2/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11309927 | 0.89 | LMNA (0.63) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6938467 | 0.88 | LMNA (0.58) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL196606 | 0.87 | TDP1 (0.70) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8818892 | 0.86 | TDP1 (0.68) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL22187262 | 0.82 | TP53 (0.68) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL29620075 | 0.82 | TP53 (0.68) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8761688 | 0.81 | TDP1 (0.67) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11844234 | 0.81 | TDP1 (0.62) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11448629 | 0.80 | SMN1; SMN2 (0.50) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL11665975 | 0.80 | APEX1 (0.60) | TDP1L3MBTL1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340489-A | Reducing the friction between two metal moving surfaces at high temperature | THE DOW CHEMICAL COMPANY (US) | 1994-08-23 | — | — | US | disclosed |
| US-5204011-A | Lubricants containing aryl arenesulfonates as lubricity additives | THE DOW CHEMICAL COMPANY (US) | 1993-04-20 | — | — | US | disclosed |