Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437299 | 0.89 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9311721 | 0.84 | AGTR1 (0.52) | LMNAAGTR1AGTR2 | |
| SCHEMBL9437285 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9844152 | 0.82 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL9844103 | 0.82 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8133913 | 0.75 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9146900 | 0.75 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL683401 | 0.75 | AGTR1 (0.74) | AGTR1AGTR2 | |
| SCHEMBL9844120 | 0.75 | PDE4A (0.65) | AGTR1AGTR2 | |
| SCHEMBL9558451 | 0.74 | AGTR1 (0.48) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296480-A | Angiotensin II receptor blocking 2,3,6-substituted 5,6,7,8-tetra-hydro-pyrido[4,3]pyrimidin-4(3H)-ones | AMERICAN CYANAMID COMPANY (US) | 1994-03-22 | — | — | US | claimed |