Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143606 | 0.81 | KCNH2 (0.40) | TOP2ATOP2B | |
| SCHEMBL143726 | 0.79 | TOP2A (0.39) | TOP2ATOP2B | |
| SCHEMBL142409 | 0.78 | GSK3B (0.37) | TOP2ATOP2B | |
| SCHEMBL3134076 | 0.77 | KCNH2 (0.38) | TOP2ATOP2B | |
| SCHEMBL143976 | 0.77 | GSK3B (0.36) | TOP2ATOP2B | |
| SCHEMBL3337171 | 0.77 | KCNH2 (0.41) | — | |
| SCHEMBL144443 | 0.77 | GSK3B (0.36) | TOP2ATOP2B | |
| SCHEMBL140634 | 0.77 | PIM1 (0.36) | TOP2ATOP2B | |
| SCHEMBL7489369 | 0.77 | STAT3 (0.40) | TOP2ATOP2B | |
| Win-57294 SCHEMBL9310002 | 0.76 | TOP2A (1.00) | TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334595-A | Anticarcinogenic agents; cytolysis | STERLING WINTHROP INC. (US) | 1994-08-02 | — | — | US | disclosed |