2,5-Xylidine

2,5-Xylidine

SCHEMBL9308900

COc1ccc(C)cc1N.Cc1ccc(C)c(N)c1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.84
CYP3A4 P08684 3/20 0.84
TDP1 Q9NUW8 5/20 0.68
ACHE P22303 1/20 0.54
THRB P10828 2/20 0.52
MAPT P10636 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
GAA P10253 3/20 0.50
TUBB4A P04350 2/20 0.47
TUBB P07437 2/20 0.47
TUBA3C P0DPH7 2/20 0.47
TUBA1B P68363 2/20 0.47
TUBA4A P68366 2/20 0.47
TUBB4B P68371 2/20 0.47
TUBB3 Q13509 2/20 0.47
TUBB2A Q13885 2/20 0.47
TUBB8 Q3ZCM7 2/20 0.47
TUBA3E Q6PEY2 2/20 0.47
TUBA1A Q71U36 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29495045 0.92 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1ACHETHRB
SCHEMBL55544 0.92 ALDH1A1 (1.00) ALDH1A1CYP3A4TDP1ACHETHRB
Hydrochloric Acid SCHEMBL10706930 0.90 ALDH1A1 (0.95) ALDH1A1CYP3A4TDP1ACHETHRB
2,5-Xylidine SCHEMBL70824 0.82
Sulfuric Acid SCHEMBL10957580 0.81 ALDH1A1 (0.78) ALDH1A1CYP3A4TDP1ACHETHRB
2,5-Xylidine SCHEMBL28157262 0.80 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1ACHETHRB
2,5-Xylidine SCHEMBL27942436 0.80 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1ACHETHRB
2,5-Xylidine SCHEMBL2869916 0.80 ALDH1A1 (0.94) ALDH1A1CYP3A4TDP1ACHETHRB
SCHEMBL11354738 0.79 ALDH1A1 (0.75) ALDH1A1CYP3A4TDP1ACHETHRB
Orthocresol SCHEMBL11881671 0.79 ALDH1A1 (0.68) ALDH1A1CYP3A4TDP1ACHETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5298607-A Reactive dyes for cotton CIBA-GEIGY CORPORATION (US) 1994-03-29 US disclosed
US-4996304-A For low temperature dyeing and printing of cellulose fibers; colorfastness CIBA-GEIGY CORPORATION (US) 1991-02-26 US disclosed