Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311058 | 0.95 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9310307 | 0.89 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL9310578 | 0.85 | AGTR1 (0.49) | AGTR1 | |
| Ripisartan SCHEMBL489673 | 0.84 | AGTR1 (0.73) | AGTR1 | |
| SCHEMBL9309079 | 0.83 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL9308719 | 0.83 | AGTR1 (0.50) | AGTR1 | |
| SCHEMBL9308164 | 0.82 | — | — | |
| SCHEMBL9308556 | 0.82 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9309186 | 0.81 | AGTR1 (0.49) | AGTR1 | |
| SCHEMBL9309068 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | claimed |
| US-5358950-A | Useful in treatment of cardiovascular diseases | LABORATOIRES UPSA (FR) | 1994-10-25 | — | — | US | disclosed |