Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.78 |
| ▸ | SPR | P35270 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229595 | 0.88 | MAPK1 (1.00) | MAPK1SPRL3MBTL1CDK4CCND1 | |
| SCHEMBL8339625 | 0.84 | MAPK1 (0.56) | MAPK1SPRL3MBTL1NOTUMKMT2A | |
| SCHEMBL9310613 | 0.84 | MAPK1 (0.57) | MAPK1SPRSMN1; SMN2 | |
| SCHEMBL8341634 | 0.84 | MAPK1 (0.55) | MAPK1SPRL3MBTL1NOTUMKMT2A | |
| SCHEMBL9310473 | 0.81 | MAPK1 (0.68) | MAPK1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL15168106 | 0.81 | LMNA (0.59) | MAPK1SPRNOTUMKMT2ALMNA | |
| SCHEMBL15167773 | 0.81 | MAPK1 (0.52) | MAPK1SPRL3MBTL1NOTUMKMT2A | |
| SCHEMBL11791537 | 0.78 | MAPK1 (0.56) | MAPK1L3MBTL1CDK4CCND1AKR1C4 | |
| SCHEMBL1420155 | 0.76 | KMT2A (0.61) | MAPK1L3MBTL1NOTUMKMT2ANPC1 | |
| SCHEMBL2402900 | 0.76 | NOTUM (0.57) | MAPK1SPRL3MBTL1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321002-A | Herbicidal derivatives of 2-(1-aryl-4-cyano-5-pyrazolylmethyleneiminooxy)alkanoic acids | FMC CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |