Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767079 | 0.94 | NOTUM (0.56) | NOTUMHPGDCASP3CASP6SENP8 | |
| SCHEMBL578262 | 0.94 | NOTUM (0.56) | NOTUMHPGDCASP3CASP6SENP8 | |
| SCHEMBL29385722 | 0.94 | NOTUM (0.56) | NOTUMHPGDCASP3CASP6SENP8 | |
| Water SCHEMBL9309686 | 0.92 | NOTUM (0.55) | NOTUMHPGDCASP3CASP6SENP8 | |
| Water SCHEMBL30404181 | 0.92 | NOTUM (0.55) | NOTUMHPGDCASP3CASP6SENP8 | |
| SCHEMBL19224526 | 0.85 | CYP1A2 (0.52) | NOTUMHPGDCASP3CASP6SENP8 | |
| SCHEMBL5502340 | 0.80 | CES1 (0.69) | NOTUMHPGDCASP3CASP6SENP8 | |
| Trifluoroacetic Acid SCHEMBL28135461 | 0.80 | NOTUM (0.51) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| SCHEMBL4994391 | 0.79 | KMT2A (0.53) | NOTUMHPGDCASP3CASP6SENP8 | |
| SCHEMBL30544986 | 0.79 | NOTUM (0.42) | NOTUMHPGDGAACHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310935-A | Optically active 5-oxygenated (3S)-1,3-dimethyloxindole-3-acetic acids | PHARMAGROUP INTERNATIONAL (US) | 1994-05-10 | — | — | US | disclosed |