Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385722 | 1.00 | NOTUM (0.56) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| SCHEMBL16767079 | 1.00 | NOTUM (0.56) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| Water SCHEMBL30404181 | 0.98 | NOTUM (0.55) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| Water SCHEMBL9309686 | 0.98 | NOTUM (0.55) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| Methoxymethane SCHEMBL9309030 | 0.94 | NOTUM (0.51) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| SCHEMBL19224526 | 0.90 | CYP1A2 (0.52) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| SCHEMBL5502340 | 0.85 | CES1 (0.69) | NOTUMHPGDKMT2ACASP3CASP6 | |
| Trifluoroacetic Acid SCHEMBL28135461 | 0.85 | NOTUM (0.51) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| SCHEMBL30544986 | 0.84 | NOTUM (0.42) | NOTUMHPGDCHRNB4CHRNA3BRPF1 | |
| SCHEMBL4994391 | 0.84 | KMT2A (0.53) | NOTUMHPGDBRPF1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 832 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754878-A | Quinazoline derivative with broad-spectrum anti-tumor activity as well as preparation method and application thereof | 成都安博力善生物科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| US-11603373-B2 | TDO2 and IDO1 inhibitors | GENENTECH, INC. (US) | 2023-03-14 | — | — | US | claimed |
| US-11542540-B2 | Control nucleic acids, and compositions, kits, and uses thereof | Life Technologies Corporation (US) | 2023-01-03 | — | — | US | claimed |
| EP-3436017-B1 | PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | MERCK SHARP & DOHME (US) | 2020-09-23 | — | — | EP | claimed |
| EP-3645533-A1 | TDO2 AND IDO1 INHIBITORS | Genentech, Inc. (US) | 2020-05-06 | — | — | EP | claimed |
| US-20200131563-A1 | CONTROL NUCLEIC ACIDS, AND COMPOSITIONS, KITS, AND USES THEREOF | Life Technologies Corporation | 2020-04-30 | — | — | US | claimed |
| US-20200123163-A1 | TDO2 and IDO1 Inhibitors | GENENTECH, INC. | 2020-04-23 | — | — | US | claimed |
| US-10544147-B2 | Purine inhibitors of human phosphatidylinositol 3-kinase delta | MERCK SHARP & DOHME CORP. (US) | 2020-01-28 | — | — | US | claimed |
| WO-2019005559-A1 | TDO2 AND IDO1 INHIBITORS | GENENTECH, INC. (US) | 2019-01-03 | — | — | WO | claimed |
| WO-2018231818-A1 | CONTROL NUCLEIC ACIDS, AND COMPOSITIONS, KITS, AND USES THEREOF | Life Technologies Corporation (US) | 2018-12-20 | — | — | WO | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| US-20020032191-A1 | 6-phenylpyridyl-2-amine derivatives useful as NOS inhibitors | LOWE JOHN A (US) | 2002-03-14 | — | — | US | claimed |
| CN-1288460-A | Process for preparing 3-methyl-2-oxoindoline | MEDICAL INFORMATION SERVICES I (JP) | 2001-03-21 | — | — | CN | claimed |
| US-5387631-A | A dinitro-, diaminoalkane rubber component; rebound resilience, skid resistance and fuel savings | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1995-02-07 | — | — | US | claimed |
| EP-0480969-A4 | AMINO ACID ANALOG CCK ANTAGONISTS | — | 1993-01-07 | — | — | EP | claimed |
| EP-0480969-A1 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-04-22 | — | — | EP | claimed |
| WO-1991000725-A2 | AMINO ACID ANALOG CCK ANTAGONISTS | ABBOTT LABORATORIES (US) | 1991-01-24 | — | — | WO | claimed |
| US-4822844-A | MODIFIED WITH NITROGEN COMPOUND CONTAINING EITHER OXYGEN OR SULFUR AS BRANCHING OR END GROUP | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1989-04-18 | — | — | US | claimed |
| US-4647625-A | Process for modifying conjugated diene polymers | NIPPON ZEON CO., LTD. (JP) | 1987-03-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544147-B2 | Purine inhibitors of human phosphatidylinositol 3-kinase delta | PIK3CD, PIK3CA, PI4KA | NOTUM 2689/4885HPGD 831/4885CHRNB4 1068/4885 |
| US-20020032191-A1 | 6-phenylpyridyl-2-amine derivatives useful as NOS inhibitors | NOS1, NOS2, NOS3 | NOTUM 1951/4885HPGD 192/4885CHRNB4 171/4885 |
| US-11603373-B2 | TDO2 and IDO1 inhibitors | IDO1, TDO2, IDO2 | NOTUM 4290/4885HPGD 432/4885CHRNB4 3956/4885 |
| US-20200123163-A1 | TDO2 and IDO1 Inhibitors | IDO1, TDO2, IDO2 | NOTUM 4290/4885HPGD 432/4885CHRNB4 3956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.