SCHEMBL9309370

SCHEMBL9309370

O=C(O)/C=C(\CCCO)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.50
TSHR P16473 1/20 0.50
CAMK2A Q9UQM7 1/20 0.46
GPR84 Q9NQS5 1/20 0.37
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8951262 1.00 KDM4E (0.50) KDM4ETSHRCAMK2AGPR84FFAR1
SCHEMBL8951267 1.00 KDM4E (0.50) KDM4ETSHRCAMK2AGPR84FFAR1
Ammonia Solution, Strong SCHEMBL9744283 0.91 KDM4E (0.46) KDM4ETSHRCAMK2AGPR84FFAR1
SCHEMBL10932417 0.87 TSHR (0.56) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL9410888 0.85 KDM4E (0.54) KDM4ETSHRCAMK2AFNTAFNTB
SCHEMBL4532099 0.85 KDM4E (0.54) KDM4ETSHRCAMK2AFNTAFNTB
SCHEMBL19745932 0.85 TSHR (0.54) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL5981768 0.85 KDM4E (0.54) KDM4ETSHRCAMK2AFNTAFNTB
SCHEMBL9410883 0.85 KDM4E (0.54) KDM4ETSHRCAMK2AFNTAFNTB
SCHEMBL9435681 0.85 TSHR (0.54) KDM4ETSHRGPR84FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5362819-A Polyester-flexible polymer block copolymers and mixtures thereof GENCORP INC. (US) 1994-11-08 US claimed
CN-111973797-B Non-invasive implantation high-viscosity adhesive material for orthopedics department and preparation method and application thereof 湖南奥星生物医药股份有限公司 2022-06-03 CN disclosed
CN-111973797-A Non-invasive implantation high-viscosity adhesive material for orthopedics department and preparation method and application thereof 曹建中 2020-11-24 CN disclosed