Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9744283

N.N.O=C(O)/C=C(/CCCCO)C(=O)O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
TSHR P16473 1/20 0.46
GPR84 Q9NQS5 1/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
CAMK2A Q9UQM7 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.31
FOLH1 Q04609 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8951262 0.91 KDM4E (0.50) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL8951267 0.91 KDM4E (0.50) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL9309370 0.91 KDM4E (0.50) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL10932417 0.89 TSHR (0.56) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL9435681 0.86 TSHR (0.54) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL19745932 0.86 TSHR (0.54) KDM4ETSHRGPR84FFAR1FFAR4
Cetostearyl Alcohol SCHEMBL1171828 0.85 TSHR (0.45) TSHRGPR84FFAR1FFAR4SMN1; SMN2
SCHEMBL10052700 0.82 TSHR (0.56) KDM4ETSHRGPR84FFAR1FFAR4
SCHEMBL5981768 0.81 KDM4E (0.54) KDM4ETSHRFNTAFNTBCAMK2A
SCHEMBL4532099 0.81 KDM4E (0.54) KDM4ETSHRFNTAFNTBCAMK2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5101045-A Hydrogenation of Maleic Anhydride or Acid BASF AKTIENGESELLSCHAFT (DE) 1992-03-31 US disclosed