Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673569 | 0.85 | CA2 (0.59) | L3MBTL1MAPK1TDP1GAATSHR | |
| SCHEMBL22187156 | 0.85 | CA2 (0.59) | L3MBTL1MAPK1TDP1GAATSHR | |
| SCHEMBL11844829 | 0.84 | CA12 (0.56) | L3MBTL1MAPK1TDP1GAATSHR | |
| SCHEMBL23361660 | 0.83 | CA12 (0.46) | L3MBTL1MAPK1TDP1GAATSHR | |
| SCHEMBL11701267 | 0.82 | KAT6A (0.47) | F2KAT6APLA2G4B | |
| SCHEMBL30579858 | 0.82 | CA2 (0.62) | MAPK1TSHRCA12CA1CA2 | |
| SCHEMBL22187321 | 0.82 | CA2 (0.62) | MAPK1TSHRCA12CA1CA2 | |
| SCHEMBL11591245 | 0.80 | CA12 (0.68) | L3MBTL1MAPK1TSHRCA12CA1 | |
| SCHEMBL22187520 | 0.79 | CA2 (0.53) | L3MBTL1MAPK1TDP1GAATSHR | |
| SCHEMBL29671358 | 0.79 | CA2 (0.53) | L3MBTL1MAPK1TDP1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340489-A | Reducing the friction between two metal moving surfaces at high temperature | THE DOW CHEMICAL COMPANY (US) | 1994-08-23 | — | — | US | disclosed |