Hydroxyamine

Hydroxyamine

SCHEMBL9309450

NO.O=S(=O)(O)OCCO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.33
TSHR P16473 4/20 0.33
FNTA P49354 2/20 0.33
FNTB P49356 2/20 0.33
MAPK1 P28482 1/20 0.33
CA1 P00915 8/20 0.32
CA9 Q16790 8/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CA4 P22748 3/20 0.31
CA6 P23280 3/20 0.31
CA5A P35218 3/20 0.31
CA7 P43166 3/20 0.31
CA5B Q9Y2D0 3/20 0.31
CA12 O43570 2/20 0.31
CA3 P07451 2/20 0.31
CA14 Q9ULX7 2/20 0.31
NT5E P21589 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126225 0.94
SCHEMBL27837209 0.92
SCHEMBL3280242 0.92
SCHEMBL27572660 0.92
SCHEMBL11876704 0.92
Ethylene Glycol SCHEMBL20360050 0.92 TSHR (0.35) CA2TSHRFNTAFNTBMAPK1
Sulfuric Acid SCHEMBL8718734 0.92 CA5A (0.35) CA2TSHRFNTAFNTBMAPK1
Water SCHEMBL3913449 0.92
Ammonia Solution, Strong SCHEMBL3497099 0.92
Water SCHEMBL15740533 0.89 TSHR (0.33) CA2TSHRFNTAFNTBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5322948-A Reacting unsaturated diacid or derivative with hydroxylamine or a salt thereof to form N-hydroxy-2-aminobutane diacid derivative HOECHST CELANESE CORPORATION (US) 1994-06-21 US disclosed
EP-0511446-A2 Process for preparing pyridinecarboxylic acid derivatives HOECHST CELANESE CORPORATION (US) 1992-11-04 EP disclosed