Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473992 | 0.92 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9309139 | 0.92 | AGTR1 (0.40) | AGTR1AGTR2EDNRA | |
| Water SCHEMBL9311609 | 0.92 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9309585 | 0.90 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9311339 | 0.90 | AGTR1 (0.40) | AGTR1AGTR2EDNRA | |
| SCHEMBL9309267 | 0.90 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9309579 | 0.90 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9310187 | 0.89 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9309876 | 0.89 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9309857 | 0.89 | AGTR1 (0.39) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | claimed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | claimed |
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |