Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15219995 | 0.84 | CES1 (0.50) | CES1NOS2PLK4CHEK1AURKA | |
| SCHEMBL15395745 | 0.78 | NOS2 (0.39) | CES1NOS2PLK4CHEK1AURKA | |
| SCHEMBL1747122 | 0.73 | — | — | |
| SCHEMBL3036634 | 0.71 | CES1 (0.61) | CES1PLK4CHEK1AURKADAPK3 | |
| SCHEMBL6331465 | 0.70 | USP2 (0.47) | CES1NOS2PLK4CHEK1AURKA | |
| SCHEMBL9594662 | 0.68 | HPGD (0.51) | CES1PTPRCLMNA | |
| SCHEMBL17225406 | 0.67 | NOS2 (0.45) | CES1NOS2PLK4CHEK1AURKA | |
| SCHEMBL2433947 | 0.67 | KMT2A (0.45) | CES1NOS2PLK4CHEK1AURKA | |
| SCHEMBL2433949 | 0.67 | KMT2A (0.45) | CES1NOS2PLK4CHEK1AURKA | |
| SCHEMBL18730188 | 0.67 | CES1 (0.46) | CES1NOS2USP2PTPRCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276039-A | Insecticides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| EP-0363051-A1 | Substituted indazole arthropodicides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-04-11 | — | — | EP | disclosed |