Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859391 | 0.93 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL9309889 | 0.86 | AGTR1 (0.55) | AGTR1 | |
| SCHEMBL9312340 | 0.86 | AGTR1 (0.54) | AGTR1 | |
| SCHEMBL9695376 | 0.84 | AGTR1 (0.46) | AGTR1 | |
| SCHEMBL9318947 | 0.82 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9693668 | 0.81 | AGTR1 (0.48) | AGTR1 | |
| SCHEMBL9311404 | 0.81 | AGTR1 (0.59) | AGTR1 | |
| SCHEMBL9310688 | 0.81 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9310042 | 0.81 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9309381 | 0.81 | AGTR1 (0.64) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |