Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309034 | 0.94 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9309861 | 0.93 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9694793 | 0.93 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9310213 | 0.93 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL9309675 | 0.92 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9311410 | 0.92 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9859431 | 0.92 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9310101 | 0.90 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9310878 | 0.90 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9309799 | 0.90 | AGTR1 (0.41) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |