Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 6/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 3/20 | 0.55 |
| ▸ | TK1 | P04183 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | EDNRA | P25101 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1981357 | 0.94 | HPRT1 (0.56) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL21050282 | 0.94 | HPRT1 (0.56) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL30150327 | 0.94 | HPRT1 (0.56) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL1981358 | 0.94 | HPRT1 (0.56) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL6538609 | 0.94 | HPRT1 (0.56) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL10647016 | 0.93 | HPRT1 (0.53) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL9308659 | 0.93 | HPRT1 (0.57) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL9309261 | 0.93 | HPRT1 (0.57) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL9019956 | 0.91 | HPRT1 (0.57) | HPRT1ADORA3PNPTK1BLM | |
| SCHEMBL9019958 | 0.91 | HPRT1 (0.57) | HPRT1ADORA3PNPTK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |