Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 10/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADA | P00813 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309083 | 0.97 | IDO1 (0.48) | IDO1ALDH1A1MEN1KMT2ANPC1 | |
| Oxalic Acid SCHEMBL9311425 | 0.90 | IDO1 (0.57) | IDO1ALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL9310694 | 0.87 | IDO1 (0.61) | IDO1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9309785 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Oxalic Acid SCHEMBL9309837 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9309862 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9309825 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9309600 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9309553 | 0.77 | IDO1 (0.45) | IDO1ALDH1A1MEN1KMT2AHRH1 | |
| Oxalic Acid SCHEMBL9311070 | 0.76 | HRH1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308848-A | Side effect reduction | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0452107-A1 | Pyrimidinedione derivatives and antiarrythmic agents containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-10-16 | — | — | EP | disclosed |