⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309342 | 0.94 | AGTR1 (0.42) | — | |
| SCHEMBL9309479 | 0.92 | AGTR1 (0.48) | — | |
| SCHEMBL9309270 | 0.91 | — | — | |
| SCHEMBL9309850 | 0.90 | — | — | |
| SCHEMBL9309392 | 0.88 | AGTR1 (0.51) | — | |
| SCHEMBL9694822 | 0.85 | AGTR1 (0.57) | — | |
| SCHEMBL9309349 | 0.84 | — | — | |
| SCHEMBL9310994 | 0.83 | AGTR1 (0.61) | — | |
| SCHEMBL9678069 | 0.83 | — | — | |
| SCHEMBL9309485 | 0.82 | AGTR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |