Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309789 | 0.96 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL9859420 | 0.95 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9309669 | 0.94 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9310870 | 0.94 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9309025 | 0.94 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9310092 | 0.94 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9694909 | 0.93 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9309381 | 0.93 | AGTR1 (0.64) | AGTR1 | |
| SCHEMBL9308989 | 0.93 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9309633 | 0.93 | AGTR1 (0.64) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374646-A | Treatment or prophylasix of hypertension and diseases associated with cognitive disorders | GLAXO GROUP LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| CN-1052672-A | Benzofuran derivative | GLAXO GROUP LTD (GB) | 1991-07-03 | — | — | CN | disclosed |
| EP-0434249-A2 | Benzofuran derivatives | GLAXO GROUP LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |