Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.52 |
| ▸ | TK1 | P04183 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HBB | P68871 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309777 | 1.00 | PNP (0.53) | PNPADORA3HPRT1TK1BLM | |
| SCHEMBL9309760 | 1.00 | PNP (0.53) | PNPADORA3HPRT1TK1BLM | |
| SCHEMBL9471442 | 0.92 | ADORA3 (0.54) | PNPADORA3HPRT1TK1BLM | |
| Lobucavir SCHEMBL2506573 | 0.90 | HPRT1 (0.53) | PNPADORA3HPRT1TK1BLM | |
| Lobucavir SCHEMBL51919 | 0.90 | HPRT1 (0.53) | PNPADORA3HPRT1TK1BLM | |
| Lobucavir SCHEMBL598707 | 0.90 | HPRT1 (0.53) | PNPADORA3HPRT1TK1BLM | |
| Lobucavir SCHEMBL7166488 | 0.90 | HPRT1 (0.53) | PNPADORA3HPRT1TK1BLM | |
| Lobucavir SCHEMBL6742530 | 0.90 | HPRT1 (0.53) | PNPADORA3HPRT1TK1BLM | |
| Lobucavir SCHEMBL5990162 | 0.90 | HPRT1 (0.53) | PNPADORA3HPRT1TK1BLM | |
| Lobucavir SCHEMBL10460499 | 0.90 | HPRT1 (0.53) | PNPADORA3HPRT1TK1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374625-A | Bis/hydroxymethyl/cycloalkyl derivatives; viricides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0468352-A2 | Novel nucleic acid derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-01-29 | — | — | EP | disclosed |