Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9308926 | 0.88 | AGTR1 (0.38) | AGTR1AGTR2PPARG | |
| SCHEMBL9308540 | 0.77 | MEN1 (0.45) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9347539 | 0.76 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL9402081 | 0.71 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9402247 | 0.71 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL12081125 | 0.70 | PPARG (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL12079721 | 0.70 | PPARG (0.44) | AGTR1PPARG | |
| SCHEMBL12080748 | 0.69 | PPARG (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL9235907 | 0.69 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9032421 | 0.69 | AGTR1 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371226-A | Hypotensive agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-12-06 | — | — | US | disclosed |