Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | CES1 | P23141 | 5/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9310269 | 0.89 | ESR1 (0.56) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL9310053 | 0.89 | PTGS2 (0.52) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL4326009 | 0.88 | ESR1 (0.64) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL9310275 | 0.83 | ESR1 (0.50) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL4961440 | 0.83 | PTGS2 (0.71) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL23641321 | 0.83 | ESR1 (0.50) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL8615209 | 0.82 | ESR1 (0.81) | ESR1PTGS2ESR2CYP19A1PSMB1 | |
| SCHEMBL9310232 | 0.82 | ESR1 (0.58) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL9317931 | 0.80 | ESR1 (0.56) | ESR1PTGS2CES2CES1ESR2 | |
| SCHEMBL28098734 | 0.80 | ESR1 (0.56) | ESR1PTGS2CES2CES1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327191-A | THEN AMINATING | RHONE-POULENC INDUSTRIES (FR) | 1982-04-27 | — | — | US | claimed |
| EP-0025385-A1 | Preparation of anion-exchange resins by bromination of vinylaromatic polymers, and products obtained | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-03-18 | — | — | EP | claimed |
| US-5326489-A | Sulfonated polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0523300-B1 | Electrorheological fluids | NIPPON CATALYTIC CHEM IND (JP) | 1994-01-19 | — | — | EP | disclosed |
| EP-0523300-A1 | Electrorheological fluids | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1993-01-20 | — | — | EP | disclosed |
| EP-0025385-B1 | PREPARATION OF ANION-EXCHANGE RESINS BY BROMINATION OF VINYLAROMATIC POLYMERS, AND PRODUCTS OBTAINED | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025385-A1 | Preparation of anion-exchange resins by bromination of vinylaromatic polymers, and products obtained | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1981-03-18 | — | — | EP | disclosed |