Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695201 | 1.00 | SPHK1 (0.47) | SPHK1KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL9310460 | 1.00 | SPHK1 (0.47) | SPHK1KDM1AMAOBSLC6A2SLC6A4 | |
| SCHEMBL628247 | 0.89 | TSHR (0.46) | SLC6A2SLC6A4SLC6A3TP53HTR2C | |
| SCHEMBL5144848 | 0.81 | CNR2 (0.49) | SLC6A2SLC6A4SLC6A3TP53HTR2C | |
| SCHEMBL5146562 | 0.81 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3TP53HTR2C | |
| SCHEMBL20868748 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3TP53HTR2C | |
| SCHEMBL8596798 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3TP53HTR2C | |
| SCHEMBL20783736 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3TP53HTR2C | |
| SCHEMBL8597881 | 0.80 | HTR2C (0.61) | SPHK1KDM1AMAOBHTR2C | |
| SCHEMBL8596799 | 0.80 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3TP53HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447828-B1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF AG (DE) | 1994-05-04 | — | — | EP | claimed |
| EP-0447828-A1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1991-09-25 | — | — | EP | claimed |
| US-9783494-B2 | Glucagon antagonists | METABASIS THERAPEUTICS, INC. (US) | 2017-10-10 | — | — | US | disclosed |
| EP-0447828-B1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF AG (DE) | 1994-05-04 | — | — | EP | disclosed |
| US-5290806-A | 4-(4-tert-butylphenyl) cyclohexylamines, and fungicides containing same | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-01 | — | — | US | disclosed |
| EP-0447828-A1 | 4-(4-Tert-Butylphenyl)cyclohexylamines and fungicides containing them | BASF Aktiengesellschaft (DE) | 1991-09-25 | — | — | EP | disclosed |