Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144848 | 0.91 | CNR2 (0.49) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL5146562 | 0.91 | SLC6A2 (0.46) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL9310477 | 0.89 | SPHK1 (0.47) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL8596799 | 0.89 | SLC6A2 (0.40) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL9310460 | 0.89 | SPHK1 (0.47) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL8596798 | 0.89 | SLC6A2 (0.40) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL8695201 | 0.89 | SPHK1 (0.47) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL20868748 | 0.89 | SLC6A2 (0.40) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL20783736 | 0.89 | SLC6A2 (0.40) | TSHRSLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL4329015 | 0.89 | SLC6A2 (0.49) | TSHRSLC6A2SLC6A4SLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344279-B | Microbiocidal picolinamide derivatives | 先正达参股股份有限公司 | 2023-07-07 | — | — | CN | disclosed |
| EP-3645626-A1 | POLYPROPYLENE COMPOSITION WITH EXCELLENT SURFACE APPEARANCE | Borealis AG (AT) | 2020-05-06 | — | — | EP | disclosed |
| WO-2019002078-A1 | POLYPROPYLENE COMPOSITION WITH EXCELLENT SURFACE APPEARANCE | BOREALIS AG (AT) | 2019-01-03 | — | — | WO | disclosed |
| WO-2017021292-A1 | POLYPROPYLENE COMPOSITION SUITABLE FOR FOAMED SHEETS AND ARTICLES | REACH PLASTIC INDUSTRIAL CO., LTD. (TW) | 2017-02-09 | — | — | WO | disclosed |
| WO-2016071384-A2 | LONG-CHAIN BRANCHED POLYPROPYLENE FOR FOAM APPLICATION | BOREALIS AG (AT) | 2016-05-12 | — | — | WO | disclosed |
| WO-2016071388-A2 | LONG-CHAIN BRANCHED POLYPROPYLENE FOR FILM APPLICATION | BOREALIS AG (AT) | 2016-05-12 | — | — | WO | disclosed |
| WO-2015181106-A1 | A PROCESS FOR TREATMENT OF POLYMERS USING A SPOUTED BED MIXER | BOREALIS AG (AT) | 2015-12-03 | — | — | WO | disclosed |
| EP-2603548-A1 | EASY TEAR POLYPROPYLENE FILM WITHOUT NOTCH | Borealis AG (AT) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012020106-A1 | EASY TEAR POLYPROPYLENE FILM WITHOUT NOTCH | BOREALIS AG (AT) | 2012-02-16 | — | — | WO | disclosed |
| US-7803827-B2 | 1-N-amino-2-imidazolidinones and derivatives thereof which are effective as Kv1.5 potassium channel inhibitors providing atrial-selective antiarrhythmic agents; 1-(aminosulfonylamino)-3-[2-(4-methoxyphenyl)ethyl]-4-(3,4-dimethylphenyl)-2-imidazolidinone | WYETH LLC (US) | 2010-09-28 | — | — | US | disclosed |
| US-7504517-B2 | Kv1.5 potassium channel inhibitors | WYETH (US) | 2009-03-17 | — | — | US | disclosed |
| US-20090069342-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2009-03-12 | — | — | US | disclosed |
| US-20070299120-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
| US-4952720-A | Ortho-substituted benzyl carboxylates and fungicides which contain these compounds | BASF AKTIENGSELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299120-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNJ2, KCNK5, KCNH2 | TSHR 2546/4885SLC6A2 2149/4885SLC6A4 3407/4885 |
| US-20070299072-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNA5, KCNH1, KCNK5 | TSHR 1447/4885SLC6A2 2171/4885SLC6A4 2622/4885 |
| US-20090069342-A1 | KV1.5 POTASSIUM CHANNEL INHIBITORS | KCNJ2, KCNK5, KCNH2 | TSHR 2546/4885SLC6A2 2149/4885SLC6A4 3407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.