Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312036 | 1.00 | FNTA (0.36) | FNTAFNTBPPARGPPARAAPP | |
| SCHEMBL9312088 | 0.91 | FNTA (0.38) | FNTAFNTBPPARGPPARAAPP | |
| SCHEMBL9312094 | 0.91 | FNTA (0.38) | FNTAFNTBPPARGPPARAAPP | |
| SCHEMBL9310733 | 0.86 | FNTA (0.34) | FNTAFNTB | |
| SCHEMBL9310716 | 0.86 | FNTA (0.34) | FNTAFNTB | |
| SCHEMBL9311914 | 0.82 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL9311905 | 0.82 | FNTA (0.39) | FNTAFNTB | |
| SCHEMBL9310172 | 0.81 | GGPS1 (0.40) | FNTAFNTB | |
| SCHEMBL9310163 | 0.81 | GGPS1 (0.40) | FNTAFNTB | |
| SCHEMBL9311364 | 0.79 | KMT2A (0.41) | PPARGPPARAAPPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374628-A | Aryl and heteroaryl(phosphinylmethyl)phosphonate squalene synthetase inhibitors and method | E. R. SQUIBB & SONS, INC. (US) | 1994-12-20 | — | — | US | disclosed |
| US-5278153-A | Hypocholesterolemic or hypolipemic | E. R. SQUIBB & SONS, INC. (US) | 1994-01-11 | — | — | US | disclosed |