SCHEMBL9312079

SCHEMBL9312079

C=COC(=O)C(=Cc1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 3/20 0.59
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
MAPT P10636 6/20 0.51
HPGD P15428 5/20 0.51
LMNA P02545 4/20 0.51
HTT P42858 3/20 0.51
ALDH1A1 P00352 2/20 0.51
KDM4E B2RXH2 1/20 0.51
POLB P06746 1/20 0.51
MAPK1 P28482 1/20 0.51
NPSR1 Q6W5P4 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP2D6 P10635 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
PLA2G1B P04054 1/20 0.44
CYP1A2 P05177 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
TRPA1 O75762 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312077 1.00 AKR1C1 (0.59) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL10534387 1.00 AKR1C1 (0.59) AKR1C1MEN1KMT2AMAPTHPGD
Acetic Acid SCHEMBL27997355 0.95 AKR1C1 (0.54) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL28869390 0.82 AKT1 (0.44) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL776442 0.82 AKR1C1 (0.68) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL27997356 0.81 AKR1C1 (0.67) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL9688036 0.81 AKT1 (0.42) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL11692565 0.80 AKR1C1 (0.66) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL19278940 0.80 MEN1 (0.44) AKR1C1MEN1KMT2AMAPTHPGD
SCHEMBL776443 0.80 AKR1C1 (0.56) AKR1C1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5294484-A Multilayer element SONY CORPORATION (JP) 1994-03-15 US disclosed
EP-0181094-B1 ADHESIVE FOR CHLORINE-CONTAINING POLYMERS AND AROMATIC GROUP-CONTAINING POLYMERS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-12-13 EP disclosed
US-4880873-A HEAT RESISTANT MODIFIED ETHYLENE VINYL ALCOHOL COPOLYMERS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-11-14 US disclosed
US-4810612-A GRAFT MODIFIED POLYOLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-03-07 US disclosed
EP-0181094-A1 Adhesive for chlorine-containing polymers and aromatic group-containing polymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-05-14 EP disclosed