SCHEMBL27997356

SCHEMBL27997356

C=COC(C)=O.O=C(O)C(=Cc1ccccc1)c1ccccc1

nearest known ligand 0.67

Known targets — ChEMBL curated mechanism

ADRB2

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 4/20 0.67
AKR1C3 P42330 4/20 0.54
AKR1C2 P52895 3/20 0.54
MEN1 O00255 6/20 0.54
KMT2A Q03164 6/20 0.54
ALDH1A1 P00352 2/20 0.54
PTGS2 P35354 1/20 0.52
HPGD P15428 4/20 0.46
POLB P06746 3/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 1/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
HTT P42858 1/20 0.46
PLA2G1B P04054 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27997355 0.83 AKR1C1 (0.54) AKR1C1AKR1C3AKR1C2MEN1KMT2A
Methacrylic Acid SCHEMBL1838687 0.82 AKR1C1 (0.79) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL290469 0.82 AKR1C1 (1.00) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL39275 0.82 AKR1C1 (1.00) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL181529 0.82 AKR1C1 (1.00) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL10534387 0.81 AKR1C1 (0.59) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL9312079 0.81 AKR1C1 (0.59) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL9312077 0.81 AKR1C1 (0.59) AKR1C1AKR1C3AKR1C2MEN1KMT2A
SCHEMBL27448137 0.80 AKR1C1 (0.96) AKR1C1AKR1C3AKR1C2MEN1KMT2A
Styrene SCHEMBL381689 0.79 ALDH1A1 (0.54) AKR1C3MEN1KMT2AALDH1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104350102-B Ethylene-vinyl alcohol resin composition, multilayer structure, multilayer sheet, container, and packaging material 株式会社可乐丽 2017-02-22 CN disclosed
CN-102844185-B Process for production of multilayered structure KURARAY CO 2015-06-17 CN disclosed
CN-104350102-A Ethylene-vinyl alcohol resin composition, multilayer structure, multilayer sheet, container, and packaging material KURARAY CO 2015-02-11 CN disclosed