Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.59 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | MPC2 | O95563 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19559777 | 0.86 | FFAR1 (0.61) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL6931578 | 0.84 | FFAR1 (0.59) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL9564659 | 0.83 | FFAR1 (0.62) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL1016495 | 0.83 | FFAR1 (0.55) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL21504844 | 0.82 | FFAR1 (0.59) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL12515224 | 0.82 | FFAR1 (0.69) | PPARGFFAR1PPARACYP3A4RXRA | |
| SCHEMBL8314978 | 0.81 | FFAR1 (0.70) | PPARGFFAR1PPARACYP3A4HRH3 | |
| SCHEMBL1072226 | 0.81 | FFAR1 (0.77) | PPARGFFAR1PPARACYP3A4HRH3 | |
| SCHEMBL4089575 | 0.80 | MAPT (0.50) | PPARGFFAR1 | |
| SCHEMBL8133230 | 0.79 | FFAR1 (0.52) | PPARGFFAR1PPARACYP3A4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5330999-A | Diabetes, obesity | ADIR ET COMPAGNIE (FR) | 1994-07-19 | — | — | US | disclosed |
| US-5296605-A | 2,4-thiazolidinedione compounds | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5266582-A | Antidiabetic agents | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |
| US-5262333-A | Fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0528734-A1 | Thiazolidin-2,4-dione derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-24 | — | — | EP | disclosed |