Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 8/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9312405 | 0.80 | PPARG (0.52) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL12521793 | 0.79 | CYP3A4 (0.48) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL6600669 | 0.76 | PPARG (0.53) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL8310673 | 0.76 | FFAR1 (0.63) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL8310671 | 0.76 | FFAR1 (0.63) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL1072226 | 0.76 | FFAR1 (0.77) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL10640627 | 0.75 | FFAR1 (0.49) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL8975496 | 0.75 | MAPK1 (0.58) | HPGDPPARGFFAR1PPARAMEN1 | |
| SCHEMBL6865994 | 0.74 | HPGD (1.00) | HPGD | |
| SCHEMBL1299035 | 0.74 | HPGD (1.00) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296605-A | 2,4-thiazolidinedione compounds | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |