Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 13/20 | 1.00 |
| ▸ | PYGL | P06737 | 3/20 | 0.76 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299035 | 1.00 | HPGD (1.00) | HPGDPYGLPTPN1POLBMAOA | |
| SCHEMBL1299868 | 0.80 | HPGD (0.66) | HPGDPYGL | |
| SCHEMBL9312411 | 0.74 | HPGD (0.59) | HPGD | |
| SCHEMBL6866458 | 0.74 | HPGD (1.00) | HPGDPYGLPIM1PIM2 | |
| SCHEMBL9326976 | 0.73 | HPGD (0.80) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL9326177 | 0.73 | HPGD (0.80) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL9439756 | 0.73 | HPGD (0.57) | HPGD | |
| SCHEMBL9312842 | 0.73 | HPGD (0.61) | HPGDPTPN1POLBMAOAMAOB | |
| SCHEMBL934038 | 0.73 | HPGD (1.00) | HPGDPIM1PIM2 | |
| SCHEMBL12107393 | 0.73 | HPGD (1.00) | HPGDPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2383263-B1 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | UNIV CHOSUN IACF (KR) | 2014-04-16 | — | — | EP | disclosed |
| US-8637558-B2 | Thiazolidinedione derivative and use thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) | 2014-01-28 | — | — | US | disclosed |
| US-8637558-B2 | Thiazolidinedione derivative and use thereof | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) | 2014-01-28 | — | — | US | disclosed |
| US-20110269954-A1 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) | 2011-11-03 | — | — | US | disclosed |
| US-20110269954-A1 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, CHOSUN UNIVERSITY (KR) | 2011-11-03 | — | — | US | disclosed |
| WO-2010077101-A4 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | 조선대학교산학협력단 (KR) | 2011-01-13 | — | — | WO | disclosed |
| WO-2010090458-A2 | COMPOSITION FOR CONTROLLING HARMFUL ALGAE | 조선대학교산학협력단 (KR) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269954-A1 | NOVEL THIAZOLIDINEDIONE DERIVATIVE AND USE THEREOF | HPGD, CYP27B1, GCDH | HPGD 1/4885PYGL 1307/4885PTPN1 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.